paerucumarin biosynthesis

Lin Y, Yan Y. Biosynthesis of caffeic acid in Escherichia coli using its endogenous hydroxylase complex. Microbial Cell Factories. 2012 Apr 04;11(1):42. doi: 10.1186/1475-2859-11-42.; Drake EJ, Gulick AM. Three-dimensional Structures of Pseudomonas aeruginosa PvcA and PvcB, Two Proteins Involved in the Synthesis of 2-Isocyano-6,7-dihydroxycoumarin. Journal of Molecular Biology. 2008 Dec;384(1):193–205. doi: 10.1016/j.jmb.2008.09.027.

Metabolites

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Fe2+

Formula: Fe (55.934939)

CAS ID: 15438-31-0

Formaldehyde

Formula: CH2O (30.0105642)

CAS ID: 50-00-0

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydroxyacetone

Formula: C3H6O2 (74.0367776)

CAS ID: 116-09-6

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

succinate(2-)

Formula: C4H4O4 (116.01095839999999)

CAS ID: 56-14-4



Enzyme

EC Number name full name note
1.14.20.9 L-tyrosine isonitrile desaturase (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate,2-oxoglutarate:oxygen oxidoreductase
4.1.99.24 L-tyrosine isonitrile synthase L-tyrosine:D-ribulose-5-phosphate lyase (isonitrile-forming)


Proteins

Protein ID name full name
Q9I1L4 pvcB paerucumarin biosynthesis protein PvcB
Q9I1L5 pvcA paerucumarin biosynthesis protein PvcA