stipitatate biosynthesis

Davison J, al Fahad A, Cai M, Song Z, Yehia SY, Lazarus CM, Bailey AM, Simpson TJ, Cox RJ. Genetic, molecular, and biochemical basis of fungal tropolone biosynthesis. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7642–7. PMID: 22508998; PMCID: PMC3356636.

Metabolites

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Fe2+

Formula: Fe (55.934939)

CAS ID: 15438-31-0

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

succinate(2-)

Formula: C4H4O4 (116.01095839999999)

CAS ID: 56-14-4

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8

2,4-Dihydroxy-3,6-dimethylbenzaldehyde

Formula: C9H10O3 (166.062991)

CAS ID: 34883-14-2



Enzyme

EC Number name full name note
1.-.-.-


Proteins

Protein ID name full name
B8M9J6 tropD Cytochrome P450 monooxygenase tropD
B8M9J8 tropB FAD-dependent monooxygenase tropB
B8M9J9 tropA 3-methylorcinaldehyde synthase tropA
B8M9K5 tropC 2-oxoglutarate-dependent dioxygenase tropC