scopoletin biosynthesis

Kai K, Mizutani M, Kawamura N, Yamamoto R, Tamai M, Yamaguchi H, Sakata K, Shimizu B. Scopoletin is biosynthesized viaortho-hydroxylation of feruloyl CoA by a 2-oxoglutarate-dependent dioxygenase inArabidopsis thaliana. The Plant Journal. 2008 Sep;55(6):989–99. doi: 10.1111/j.1365-313x.2008.03568.x.

Metabolites

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Fe2+

Formula: Fe (55.934939)

CAS ID: 15438-31-0

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Psoralen

Formula: C11H6O3 (186.0316926)

CAS ID: 66-97-7

Scopoletin

Formula: C10H8O4 (192.0422568)

CAS ID: 92-61-5

feruloyl-CoA

Formula: C31H40N7O19P3S (939.131248)

CAS ID:

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

succinate(2-)

Formula: C4H4O4 (116.01095839999999)

CAS ID: 56-14-4

trans-6-hydroxyferuloyl-CoA

Formula: C31H40N7O20P3S-4 (955.126163)

CAS ID:



Enzyme

EC Number name full name note
2.1.1.-
1.14.11.61 feruloyl-CoA 6-hydroxylase feruloyl-CoA,2-oxoglutarate:oxygen oxidoreductase (6-hydroxylating)
1.14.11.62 trans-4-coumaroyl-CoA 2-hydroxylase (2E)-3-(4-hydroxyphenyl)prop-2-enoyl-CoA,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating)
2.1.1.104 caffeoyl-CoA O-methyltransferase S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase


Proteins

Protein ID name full name