Serotonin biosynthesis

Byeon Y, Park S, Kim YS, Park DH, Lee S, Back K. Light-regulated melatonin biosynthesis in rice during the senescence process in detached leaves. J Pineal Res. 2012 Aug;53(1):107–11. doi: 10.1111/j.1600-079x.2012.00976.x. PMID: 22289080.; Park S, Lee K, Kim Y, Back K. Tryptamine 5-hydroxylase-deficient Sekiguchi rice induces synthesis of 5-hydroxytryptophan and N-acetyltryptamine but decreases melatonin biosynthesis during senescence process of detached leaves. Journal of Pineal Research. 2011 Sep 02;52(2):211–6. doi: 10.1111/j.1600-079x.2011.00930.x.; Fujiwara T, Maisonneuve S, Isshiki M, Mizutani M, Chen L, Wong HL, Kawasaki T, Shimamoto K. Sekiguchi Lesion Gene Encodes a Cytochrome P450 Monooxygenase That Catalyzes Conversion of Tryptamine to Serotonin in Rice. Journal of Biological Chemistry. 2010 Apr;285(15):11308–13. doi: 10.1074/jbc.m109.091371.; Kang S, Kang K, Lee K, Back K. Characterization of tryptamine 5-hydroxylase and serotonin synthesis in rice plants. Plant Cell Rep. 2007 Nov;26(11):2009–15. doi: 10.1007/s00299-007-0405-9. PMID: 17639402.

Metabolites

Caffeoyl-CoA

Formula: C30H42N7O19P3S (929.1468972000001)

CAS ID: 53034-79-0

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

CoA

Formula: C21H36N7O16P3S (767.1152046000001)

CAS ID: 85-61-0

Feruloyl-CoA

Formula: C31H44N7O19P3S (943.1625464)

CAS ID: 142185-30-6

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

p-Coumaroyl-CoA

Formula: C30H42N7O18P3S (913.1519822000001)

CAS ID: 119785-99-8

Serotonin

Formula: C10H12N2O (176.09495819999998)

CAS ID: 50-67-9

Tryptamine

Formula: C10H12N2 (160.1000432)

CAS ID: 61-54-1



Enzyme

EC Number name full name note


Proteins

Protein ID name full name