Valine Biosynthesis

Metabolites

(R)-2,3-Dihydroxy-3-methylbutanoate

Formula: C5H10O4 (134.057906)

CAS ID: 19451-56-0

(S)-2-Acetolactate

Formula: C5H8O4 (132.0422568)

CAS ID: 71698-08-3

2-Oxoglutarate

Formula: C5H6O5 (146.0215226)

CAS ID: 328-50-7

3-Methylbutanoic acid

Formula: C5H10O2 (102.068076)

CAS ID: 503-74-2

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

L-Glutamate

Formula: C5H9NO4 (147.0531554)

CAS ID: 56-86-0

L-Valine

Formula: C5H11NO2 (117.0789746)

CAS ID: 72-18-4

NADP+

Formula: C21H29N7O17P3 (744.0832754)

CAS ID: 53-59-8

Pyruvate

Formula: C3H4O3 (88.0160434)

CAS ID: 127-17-3



Enzyme

EC Number name full name note
1.1.1.86 ketol-acid reductoisomerase (NADP+) (R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)
4.2.1.9 dihydroxy-acid dehydratase 2,3-dihydroxy-3-methylbutanoate hydro-lyase (3-methyl-2-oxobutanoate-forming)


Proteins

Protein ID name full name
A6UYF6 ilvD Dihydroxy-acid dehydratase
B7V1A6 ilvC Ketol-acid reductoisomerase (NADP(+))