Prostaglandin synthesis and regulation

Matsuura K, Shiraishi H, Hara A, Sato K, Deyashiki Y, Ninomiya M, Sakai S. Identification of a principal mRNA species for human 3alpha-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D2 11-ketoreductase activity. J Biochem. 1998 Nov;124(5):940–6. doi: 10.1093/oxfordjournals.jbchem.a022211. PMID: 9792917.

Metabolites

(5Z,13E)-11alpha-Hydroxy-9,15-dioxoprost-5,13-dienoate

Formula: C20H30O5 (350.209313)

CAS ID: 26441-05-4

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

Cortisone

Formula: C21H28O5 (360.1936638)

CAS ID: 53-06-5

Prostaglandin D2

Formula: C20H32O5 (352.2249622)

CAS ID: 41598-07-6

Prostaglandin F2alpha

Formula: C20H34O5 (354.24061140000003)

CAS ID: 551-11-1

Thromboxane A2

Formula: C20H32O5 (352.2249622)

CAS ID: 57576-52-0

20-hydroxypregn-4-en-3-one

Formula: C21H32O2 (316.24021719999996)

CAS ID: 15114-79-1



Enzyme

EC Number name full name note


Proteins

Protein ID name full name