SARS-CoV-2 replication organelle formation

Twu WI, Lee JY, Kim H, Prasad V, Cerikan B, Haselmann U, Tabata K, Bartenschlager R. Contribution of autophagy machinery factors to HCV and SARS-CoV-2 replication organelle formation. Cell Rep. 2021 Nov 23;37(8):110049. PMID: 34788596; PMCID: PMC8577994.

Metabolites



Enzyme

EC Number name full name note
3.1.13.-
2.1.1.56 mRNA (guanine-N7)-methyltransferase S-adenosyl-L-methionine:mRNA (guanine-N7)-methyltransferase
2.1.1.57 methyltransferase cap1 S-adenosyl-L-methionine:5-(N7-methyl 5-triphosphoguanosine)-(ribonucleotide)-[mRNA] 2-O-methyltransferase
2.7.1.137 phosphatidylinositol 3-kinase ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
2.7.7.48 RNA-directed RNA polymerase nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
2.7.7.50 mRNA guanylyltransferase GTP:mRNA guanylyltransferase
3.4.19.12 ubiquitinyl hydrolase 1
3.4.22.69 SARS coronavirus main proteinase
3.6.4.12 DNA helicase
3.6.4.13 RNA helicase


Proteins

Protein ID name full name