RNA Polymerase II Promoter Escape

Holstege FC, Fiedler U, Timmers HT. Three transitions in the RNA polymerase II transcription complex during initiation. EMBO J. 1997 Dec 15;16(24):7468–80. PMID: 9405375; PMCID: PMC1170346.

Metabolites

adenosine 5'-monophosphate(2-)

Formula: C10H12N5O7P (345.0474332)

CAS ID:

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:



Enzyme

EC Number name full name note
2.7.11.23 [RNA-polymerase]-subunit kinase ATP:[DNA-directed RNA polymerase] phosphotransferase
2.7.7.6 DNA-directed RNA polymerase nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed)
5.6.2.3 DNA 5'-3' helicase DNA 5'-3' helicase (ATP-hydrolysing)
5.6.2.4 DNA 3'-5' helicase DNA 3'-5' helicase (ATP-hydrolysing)


Proteins

Protein ID name full name
O13768 ptr8 General transcription and DNA repair factor IIH helicase/translocase subunit XPB
P26659 rad15 General transcription and DNA repair factor IIH helicase subunit XPD
P36594 rpb1 DNA-directed RNA polymerase II subunit rpb1
Q02061 rpb2 DNA-directed RNA polymerase II subunit RPB2
Q12126 crk1 Serine/threonine-protein kinase crk1