Processive synthesis on the lagging strand
Tsurimoto T, Stillman B. Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis. Journal of Biological Chemistry. 1991 Jan;266(3):1961–8. doi: 10.1016/s0021-9258(18)52386-3.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 3.1.-.- | |||
| 2.7.7.7 | DNA-directed DNA polymerase | deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) | |
| 5.6.2.3 | DNA 5'-3' helicase | DNA 5'-3' helicase (ATP-hydrolysing) | |
| 6.5.1.1 | DNA ligase (ATP) | poly(deoxyribonucleotide)-3'-hydroxyl:5'-phospho-poly(deoxyribonucleotide) ligase (ATP) |
Proteins
| Protein ID | name | full name |
|---|---|---|
| P12000 | cdc17 | DNA ligase 1 |
| P30316 | pol3 | DNA polymerase delta catalytic subunit |
| P39750 | rad2 | Flap endonuclease 1 |
| P87324 | cdc1 | DNA polymerase subunit delta-2 |
| Q9URU2 | dna2 | DNA replication ATP-dependent helicase/nuclease dna2 |