rRNA processing in the nucleus and cytosol
Henras AK, Plisson-Chastang C, O'Donohue MF, Chakraborty A, Gleizes PE. An overview of pre-ribosomal RNA processing in eukaryotes. Wiley Interdiscip Rev RNA. 2015 Mar;6(2):225–42. PMID: 25346433; PMCID: PMC4361047.; Boschi-Muller S, Motorin Y. Chemistry enters nucleic acids biology: enzymatic mechanisms of RNA modification. Biochemistry (Mosc). 2013 Dec;78(13):1392–404. doi: 10.1134/s0006297913130026. PMID: 24490730.; Hernandez-Verdun D, Roussel P, Thiry M, Sirri V, Lafontaine DL. The nucleolus: structure/function relationship in RNA metabolism. Wiley Interdiscip Rev RNA. 2010 Nov;1(3):415–31. doi: 10.1002/wrna.39. PMID: 21956940.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.1.1.- | |||
| 2.7.11.1 | non-specific serine/threonine protein kinase | ATP:protein phosphotransferase (non-specific) | |
| 3.1.26.5 | ribonuclease P | ||
| 3.6.4.13 | RNA helicase |
Proteins
| Protein ID | name | full name |
|---|---|---|
| O14232 | mtr4 | ATP-dependent RNA helicase mtr4 |
| O42650 | rio1 | Serine/threonine-protein kinase rio1 |
| O42957 | ulp1 | Ubiquitin-like-specific protease 1 |
| P40235 | hhp1 | Casein kinase I homolog hhp1 |
| P87120 | RNP3_SCHPO | Probable ribonuclease P protein subunit 3 |
| Q09775 | rok1 | ATP-dependent RNA helicase rok1 |
| Q10107 | mra1 | Ribosomal RNA small subunit methyltransferase mra1 |
| Q10146 | rrp6 | Exosome complex exonuclease rrp6 |
| Q10162 | bud23 | 18S rRNA (guanine-N(7))-methyltransferase bud23 |
| Q9HDY4 | YK16_SCHPO | Putative ATP-dependent RNA helicase PB1A10.06c |
| Q9HGM5 | dbp8 | ATP-dependent RNA helicase dbp8 |
| Q9P6N8 | rrp3 | ATP-dependent rRNA helicase rrp3 |
| Q9P7W5 | rio2 | Serine/threonine-protein kinase rio2 |
| Q9UTK0 | nob1 | 20S-pre-rRNA D-site endonuclease nob1 |
| Q9UU96 | grc3 | Polynucleotide 5'-hydroxyl-kinase grc3 |
| Q9Y813 | rpr2 | Ribonuclease P protein subunit rpr2 |