mRNA 3'-end processing

Proudfoot NJ, Furger A, Dye MJ. Integrating mRNA processing with transcription. Cell. 2002 Feb 22;108(4):501–12. doi: 10.1016/s0092-8674(02)00617-7. PMID: 11909521.; Wahle E, Rüegsegger U. 3'-End processing of pre-mRNA in eukaryotes. FEMS Microbiol Rev. 1999 Jun;23(3):277–95. doi: 10.1111/j.1574-6976.1999.tb00400.x. PMID: 10371034.; Zhao J, Hyman L, Moore C. Formation of mRNA 3' Ends in Eukaryotes: Mechanism, Regulation, and Interrelationships with Other Steps in mRNA Synthesis. Microbiol Mol Biol Rev. 1999 Jun;63(2):405–45. doi: 10.1128/mmbr.63.2.405-445.1999.; Moore CL, Sharp PA. Accurate cleavage and polyadenylation of exogenous RNA substrate. Cell. 1985 Jul;41(3):845–55. doi: 10.1016/s0092-8674(85)80065-9. PMID: 2408761.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:



Enzyme

EC Number name full name note
3.1.27.-
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
2.7.1.78 polynucleotide 5'-hydroxyl-kinase ATP:5'-dephosphopolynucleotide 5'-phosphotransferase
2.7.7.19 polynucleotide adenylyltransferase ATP:polynucleotide adenylyltransferase
3.6.4.13 RNA helicase


Proteins

Protein ID name full name