Ethanol oxidation

Lemasters JJ. Modulation of mitochondrial membrane permeability in pathogenesis, autophagy and control of metabolism. J Gastroenterol Hepatol. 2007 Jun;22 Suppl 1():S31–7. doi: 10.1111/j.1440-1746.2006.04643.x. PMID: 17567461.; Chen C, Lu R, Chen Y, Wang M, Chang Y, Li T, Yin S. Interaction between the Functional Polymorphisms of the Alcohol-Metabolism Genes in Protection against Alcoholism. The American Journal of Human Genetics. 1999 Sep;65(3):795–807. doi: 10.1086/302540.; Yoshida A, Davé V, Ward RJ, Peters TJ. Cytosolic aldehyde dehydrogenase (ALDH1) variants found in alcohol flushers. Ann Hum Genet. 1989 Jan;53(1):1–7. doi: 10.1111/j.1469-1809.1989.tb01116.x. PMID: 2729894.; Jörnvall H. Alcohol dehydrogenases, aldehyde dehydrogenases, and related enzymes. Alcohol. 1985 Jan;2(1):61–6. doi: 10.1016/0741-8329(85)90017-5. PMID: 3893466.; Inoue K, Nishimukai H, Yamasawa K. Purification and partial characterization of aldehyde dehydrogenase from human erythrocytes. Biochimica et Biophysica Acta (BBA) - Enzymology. 1979 Aug;569(2):117–23. doi: 10.1016/0005-2744(79)90046-9.; Lange LG, Sytkowski AJ, Vallee BL. Human liver alcohol dehydrogenase: purification, composition, and catalytic features. Biochemistry. 1976 Oct 19;15(21):4687–93. doi: 10.1021/bi00666a023. PMID: 9982.; Racker E. ALDEHYDE DEHYDROGENASE, A DIPHOSPHOPYRIDINE NUCLEOTIDE-LINKED ENZYME. Journal of Biological Chemistry. 1949 Feb;177(2):883–92. doi: 10.1016/s0021-9258(18)57033-2.

Metabolites

Acetaldehyde

Formula: C2H4O (44.0262134)

CAS ID: 75-07-0

Acetate

Formula: C2H4O2 (60.0211284)

CAS ID: 64-19-7

Ethanol

Formula: C2H6O (46.0418626)

CAS ID: 64-17-5

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

acetate

Formula: C2H3O2 (59.0133038)

CAS ID: 71-50-1

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9



Enzyme

EC Number name full name note
1.1.1.1 alcohol dehydrogenase alcohol:NAD+ oxidoreductase


Proteins

Protein ID name full name