Inhibition of replication initiation of damaged DNA by RB1/E2F1

Magenta A, Fasanaro P, Romani S, Di Stefano V, Capogrossi MC, Martelli F. Protein Phosphatase 2A Subunit PR70 Interacts with pRb and Mediates Its Dephosphorylation. Molecular and Cellular Biology. 2008 Jan 01;28(2):873–82. doi: 10.1128/mcb.00480-07.; Avni D, Yang H, Martelli F, Hofmann F, ElShamy WM, Ganesan S, Scully R, Livingston DM. Active localization of the retinoblastoma protein in chromatin and its response to S phase DNA damage. Mol Cell. 2003 Sep;12(3):735–46. doi: 10.1016/s1097-2765(03)00355-1. PMID: 14527418.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5



Enzyme

EC Number name full name note
2.7.7.-
2.7.7.7 DNA-directed DNA polymerase deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)


Proteins

Protein ID name full name