Electron transport from NADPH to Ferredoxin

Shi Y, Ghosh M, Kovtunovych G, Crooks DR, Rouault TA. Both human ferredoxins 1 and 2 and ferredoxin reductase are important for iron-sulfur cluster biogenesis. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2012 Feb;1823(2):484–92. doi: 10.1016/j.bbamcr.2011.11.002.; Sheftel AD, Stehling O, Pierik AJ, Elsässer HP, Mühlenhoff U, Webert H, Hobler A, Hannemann F, Bernhardt R, Lill R. Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11775–80. PMID: 20547883; PMCID: PMC2900682.; Grinberg AV, Hannemann F, Schiffler B, Müller J, Heinemann U, Bernhardt R. Adrenodoxin: structure, stability, and electron transfer properties. Proteins. 2000 Sep 01;40(4):590–612. doi: 10.1002/1097-0134(20000901)40:4<590::aid-prot50>3.0.co;2-p. PMID: 10899784.; Lambeth JD, Seybert DW, Lancaster JR, Salerno JC, Kamin H. Steroidogenic electron transport in adrenal cortex mitochondria. Molecular and Cellular Biochemistry. 1982 May;45(1):13–31. doi: 10.1007/bf01283159.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.18.1.6 adrenodoxin-NADP+ reductase adrenodoxin:NADP+ oxidoreductase


Proteins

Protein ID name full name