Abacavir metabolism

Yuen GJ, Weller S, Pakes GE. A review of the pharmacokinetics of abacavir. Clin Pharmacokinet. 2008;47(6):351–71. doi: 10.2165/00003088-200847060-00001. PMID: 18479171.

Metabolites

Abacavir

Formula: C14H18N6O (286.1542018)

CAS ID: 136470-78-5

Cyclopropylamine

Formula: C3H7N (57.0578462)

CAS ID: 765-30-0

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

abacavir monophosphate

Formula: C14H19N6O4P (366.12053440000005)

CAS ID: 136470-77-4



Enzyme

EC Number name full name note
1.1.1.1 alcohol dehydrogenase alcohol:NAD+ oxidoreductase


Proteins

Protein ID name full name