Methylation

Fontecave M, Atta M, Mulliez E. S-adenosylmethionine: nothing goes to waste. Trends Biochem Sci. 2004 May;29(5):243–9. doi: 10.1016/j.tibs.2004.03.007. PMID: 15130560.; Lu SC, Huang Z, Yang H, Mato JM, Avila MA, Tsukamoto H. Changes in methionine adenosyltransferase andS-adenosylmethionine homeostasis in alcoholic rat liver. American Journal of Physiology-Gastrointestinal and Liver Physiology. 2000 Jul 01;279(1):G178–85. doi: 10.1152/ajpgi.2000.279.1.g178.; Weinshilboum RM, Otterness DM, Szumlanski CL. Methylation pharmacogenetics: catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase. Annu Rev Pharmacol Toxicol. 1999;39():19–52. doi: 10.1146/annurev.pharmtox.39.1.19. PMID: 10331075.

Metabolites

Adenosine

Formula: C10H13N5O4 (267.09674980000005)

CAS ID: 58-61-7

Cacodylate

Formula: C2H7AsO2 (137.9661982)

CAS ID: 75-60-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Methanearsonous acid

Formula: CH5AsO2 (123.950549)

CAS ID: 25400-23-1

N-Methylpyridinium

Formula: C6H8N (94.06567079999999)

CAS ID: 694-56-4

Pyridine

Formula: C5H5N (79.042197)

CAS ID: 110-86-1

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

methylarsonate(1-)

Formula: CH4AsO3 (138.9376394)

CAS ID: 51952-66-0



Enzyme

EC Number name full name note
1.16.1.8 [methionine synthase] reductase [methionine synthase]-methylcob(III)alamin,S-adenosyl-L-homocysteine:NADP+ oxidoreductase
1.20.4.2 methylarsonate reductase glutathione:methylarsonate oxidoreductase
1.8.5.1 glutathione dehydrogenase (ascorbate) glutathione:dehydroascorbate oxidoreductase
2.1.1.1 nicotinamide N-methyltransferase S-adenosyl-L-methionine:nicotinamide N-methyltransferase
2.1.1.13 methionine synthase 5-methyltetrahydrofolate:L-homocysteine S-methyltransferase
2.5.1.18 glutathione transferase RX:glutathione R-transferase
3.13.2.1 adenosylhomocysteinase S-adenosyl-L-homocysteine hydrolase


Proteins

Protein ID name full name