Regulation of thyroid hormone activity

Bianco AC, Kim BW. Deiodinases: implications of the local control of thyroid hormone action. Journal of Clinical Investigation. 2006 Oct 02;116(10):2571–9. doi: 10.1172/jci29812.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

Iodide

Formula: I (126.904477)

CAS ID: 20461-54-5

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.21.99.3 thyroxine 5-deiodinase 3,3',5'-triiodo-L-thyronine,iodide:acceptor oxidoreductase (iodinating)
1.21.99.4 thyroxine 5'-deiodinase 3,3',5-triiodo-L-thyronine,iodide:acceptor oxidoreductase (iodinating)


Proteins

Protein ID name full name