Mitotic Spindle Checkpoint

Chan GK, Yen TJ. The mitotic checkpoint: a signaling pathway that allows a single unattached kinetochore to inhibit mitotic exit. Prog Cell Cycle Res. 2003;5():431–9. PMID: 14593737.; Musacchio A, Hardwick KG. The spindle checkpoint: structural insights into dynamic signalling. Nature Reviews Molecular Cell Biology. 2002 Oct;3(10):731–41. doi: 10.1038/nrm929.

Metabolites



Enzyme

EC Number name full name note
2.3.2.23 E2 ubiquitin-conjugating enzyme S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:[E2 ubiquitin-conjugating enzyme] ubiquitinyl transferase
2.3.2.24 (E3-independent) E2 ubiquitin-conjugating enzyme S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:L-lysine ubiquitinyl transferase ([E3 ubiquitin transferase]-independent)
2.7.11.21 polo kinase ATP:protein phosphotransferase (spindle-pole-dependent)
3.1.3.16 protein-serine/threonine phosphatase protein-serine/threonine-phosphate phosphohydrolase
3.6.4.12 DNA helicase


Proteins

Protein ID name full name