Serine metabolism

de Koning TJ, Klomp LW. Serine-deficiency syndromes. Curr Opin Neurol. 2004 Apr;17(2):197–204. doi: 10.1097/00019052-200404000-00019. PMID: 15021249.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

3-phospho-hydroxypyruvate

Formula: C3H2O7P (180.95381719999997)

CAS ID:

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9



Enzyme

EC Number name full name note
1.1.1.95 phosphoglycerate dehydrogenase 3-phospho-D-glycerate:NAD+ 2-oxidoreductase
3.1.3.3 phosphoserine phosphatase O-phosphoserine phosphohydrolase
4.3.1.17 L-serine ammonia-lyase L-serine ammonia-lyase (pyruvate-forming)
4.3.1.18 D-Serine ammonia-lyase D-serine ammonia-lyase (pyruvate-forming)
4.3.1.19 threonine ammonia-lyase L-threonine ammonia-lyase (2-oxobutanoate-forming)
5.1.1.18 serine racemase serine racemase


Proteins

Protein ID name full name