APC/C:Cdc20 mediated degradation of mitotic proteins

Owens TJ, Hoyt MA. The D box asserts itself. Mol Cell. 2005 Jun 10;18(6):611–2. doi: 10.1016/j.molcel.2005.05.019. PMID: 15949434.; Zachariae W, Nasmyth K. Whose end is destruction: cell division and the anaphase-promoting complex. Genes Dev. 1999 Aug 15;13(16):2039–58. doi: 10.1101/gad.13.16.2039. PMID: 10465783.

Metabolites



Enzyme

EC Number name full name note
2.3.2.23 E2 ubiquitin-conjugating enzyme S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:[E2 ubiquitin-conjugating enzyme] ubiquitinyl transferase
2.3.2.24 (E3-independent) E2 ubiquitin-conjugating enzyme S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:L-lysine ubiquitinyl transferase ([E3 ubiquitin transferase]-independent)
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
2.7.11.22 cyclin-dependent kinase ATP:cyclin phosphotransferase
2.7.11.23 [RNA-polymerase]-subunit kinase ATP:[DNA-directed RNA polymerase] phosphotransferase


Proteins

Protein ID name full name