EGFR Transactivation by Gastrin

Liebmann C. EGF receptor activation by GPCRs: an universal pathway reveals different versions. Mol Cell Endocrinol. 2011 Jan 15;331(2):222–31. doi: 10.1016/j.mce.2010.04.008. PMID: 20398727.; Dufresne M, Seva C, Fourmy D. Cholecystokinin and gastrin receptors. Physiol Rev. 2006 Jul;86(3):805–47. doi: 10.1152/physrev.00014.2005. PMID: 16816139.

Metabolites

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2



Enzyme

EC Number name full name note
2.7.10.1 receptor protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type)
2.7.11.13 protein kinase C ATP:protein phosphotransferase (diacylglycerol-dependent)
3.4.24.17 stromelysin 1


Proteins

Protein ID name full name