Heme synthesis

Severance S, Hamza I. Trafficking of heme and porphyrins in metazoa. Chem Rev. 2009 Oct;109(10):4596–616. PMID: 19764719; PMCID: PMC2769250.

Metabolites

Ammonia

Formula: NH3 (17.0265478)

CAS ID: 7664-41-7

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Etiocholanolone

Formula: C19H30O2 (290.224568)

CAS ID: 53-42-9

Fe2+

Formula: Fe (55.934939)

CAS ID: 15438-31-0

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydrogen peroxide

Formula: H2O2 (34.0054792)

CAS ID: 7722-84-1

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

dipyrromethane

Formula: C9H10N2 (146.084394)

CAS ID: 21211-65-4



Enzyme

EC Number name full name note
2.3.1.37 5-aminolevulinate synthase succinyl-CoA:glycine C-succinyltransferase (decarboxylating)
4.98.1.1 protoporphyrin ferrochelatase protoheme ferro-lyase (protoporphyrin-forming)


Proteins

Protein ID name full name