Vasopressin regulates renal water homeostasis via Aquaporins

Nedvetsky PI, Tamma G, Beulshausen S, Valenti G, Rosenthal W, Klussmann E. Regulation of aquaporin-2 trafficking. Handb Exp Pharmacol. 2009;(190):133–57. doi: 10.1007/978-3-540-79885-9_6. PMID: 19096775.; Takata K, Matsuzaki T, Tajika Y, Ablimit A, Hasegawa T. Localization and trafficking of aquaporin 2 in the kidney. Histochemistry and Cell Biology. 2008 Jun 20;130(2):197–209. doi: 10.1007/s00418-008-0457-0.; Nielsen S, Kwon T-, Frøkiær J, Agre P. Regulation and dysregulation of aquaporins in water balance disorders*. Journal of Internal Medicine. 2007 Jan;261(1):53–64. doi: 10.1111/j.1365-2796.2006.01760.x.; Nejsum LN. The renal plumbing system: aquaporin water channels. Cellular and Molecular Life Sciences. 2005 May 28;62(15):1692–706. doi: 10.1007/s00018-005-4549-x.; Nielsen S, Frøkiaer J, Marples D, Kwon TH, Agre P, Knepper MA. Aquaporins in the kidney: from molecules to medicine. Physiol Rev. 2002 Jan;82(1):205–44. doi: 10.1152/physrev.00024.2001. PMID: 11773613.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2



Enzyme

EC Number name full name note
3.6.5.2 small monomeric GTPase GTP phosphohydrolase (cell-regulating)


Proteins

Protein ID name full name