POLB-Dependent Long Patch Base Excision Repair
Liu Y, Beard WA, Shock DD, Prasad R, Hou EW, Wilson SH. DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair. J Biol Chem. 2005 Feb 04;280(5):3665–74. doi: 10.1074/jbc.m412922200. PMID: 15561706.; Cistulli C, Lavrik OI, Prasad R, Hou E, Wilson SH. AP endonuclease and poly(ADP-ribose) polymerase-1 interact with the same base excision repair intermediate. DNA Repair (Amst). 2004 Jun 03;3(6):581–91. doi: 10.1016/j.dnarep.2003.09.012. PMID: 15135726.; Ranalli TA, Tom S, Bambara RA. AP Endonuclease 1 Coordinates Flap Endonuclease 1 and DNA Ligase I Activity in Long Patch Base Excision Repair. Journal of Biological Chemistry. 2002 Nov;277(44):41715–24. doi: 10.1074/jbc.m207207200.; Prasad R, Lavrik OI, Kim SJ, Kedar P, Yang XP, Vande Berg BJ, Wilson SH. DNA polymerase beta -mediated long patch base excision repair. Poly(ADP-ribose)polymerase-1 stimulates strand displacement DNA synthesis. J Biol Chem. 2001 Aug 31;276(35):32411–4. doi: 10.1074/jbc.c100292200. PMID: 11440997.; Lavrik OI, Prasad R, Sobol RW, Horton JK, Ackerman EJ, Wilson SH. Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair. J Biol Chem. 2001 Jul 06;276(27):25541–8. doi: 10.1074/jbc.m102125200. PMID: 11340072.; Tomkinson AE, Chen L, Dong Z, Leppard JB, Levin DS, Mackey ZB, Motycka TA. Completion of base excision repair by mammalian DNA ligases. Prog Nucleic Acid Res Mol Biol. 2001;68():151–64. doi: 10.1016/s0079-6603(01)68097-8. PMID: 11554294.; Dimitriadis EK, Prasad R, Vaske MK, Chen L, Tomkinson AE, Lewis MS, Wilson SH. Thermodynamics of human DNA ligase I trimerization and association with DNA polymerase beta. J Biol Chem. 1998 Aug 07;273(32):20540–50. doi: 10.1074/jbc.273.32.20540. PMID: 9685411.; Klungland A, Lindahl T. Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). EMBO J. 1997 Jun 02;16(11):3341–8. PMID: 9214649; PMCID: PMC1169950.