RNA Polymerase II Transcription Elongation
Arndt KM, Kane CM. Running with RNA polymerase: eukaryotic transcript elongation. Trends Genet. 2003 Oct;19(10):543–50. doi: 10.1016/j.tig.2003.08.008. PMID: 14550628.; Shilatifard A, Conaway RC, Conaway JW. The RNA polymerase II elongation complex. Annu Rev Biochem. 2003;72():693–715. doi: 10.1146/annurev.biochem.72.121801.161551. PMID: 12676794.; Komarnitsky P, Cho EJ, Buratowski S. Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. Genes Dev. 2000 Oct 01;14(19):2452–60. PMID: 11018013; PMCID: PMC316976.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.7.11.23 | [RNA-polymerase]-subunit kinase | ATP:[DNA-directed RNA polymerase] phosphotransferase | |
| 2.7.7.6 | DNA-directed RNA polymerase | nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) | |
| 3.1.3.16 | protein-serine/threonine phosphatase | protein-serine/threonine-phosphate phosphohydrolase | |
| 5.6.2.3 | DNA 5'-3' helicase | DNA 5'-3' helicase (ATP-hydrolysing) | |
| 5.6.2.4 | DNA 3'-5' helicase | DNA 3'-5' helicase (ATP-hydrolysing) |
Proteins
| Protein ID | name | full name |
|---|---|---|
| O13768 | ptr8 | General transcription and DNA repair factor IIH helicase/translocase subunit XPB |
| P26659 | rad15 | General transcription and DNA repair factor IIH helicase subunit XPD |
| P36594 | rpb1 | DNA-directed RNA polymerase II subunit rpb1 |
| Q02061 | rpb2 | DNA-directed RNA polymerase II subunit RPB2 |
| Q12126 | crk1 | Serine/threonine-protein kinase crk1 |
| Q9P376 | fcp1 | RNA polymerase II subunit A C-terminal domain phosphatase |