mRNA Capping
Proudfoot NJ, Furger A, Dye MJ. Integrating mRNA processing with transcription. Cell. 2002 Feb 22;108(4):501–12. doi: 10.1016/s0092-8674(02)00617-7. PMID: 11909521.; Shatkin AJ, Manley JL. The ends of the affair: Capping and polyadenylation. Nature Structural & Molecular Biology. 2000 Oct;7(10):838–42. doi: 10.1038/79583.; Bentley D. Coupling RNA polymerase II transcription with pre-mRNA processing. Curr Opin Cell Biol. 1999 Jun;11(3):347–51. doi: 10.1016/s0955-0674(99)80048-9. PMID: 10395561.; Mizumoto K, Kaziro Y. Messenger RNA capping enzymes from eukaryotic cells. Prog Nucleic Acid Res Mol Biol. 1987;34():1–28. doi: 10.1016/s0079-6603(08)60491-2. PMID: 3326038.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.1.1.56 | mRNA (guanine-N7)-methyltransferase | S-adenosyl-L-methionine:mRNA (guanine-N7)-methyltransferase | |
| 2.7.11.23 | [RNA-polymerase]-subunit kinase | ATP:[DNA-directed RNA polymerase] phosphotransferase | |
| 2.7.7.50 | mRNA guanylyltransferase | GTP:mRNA guanylyltransferase | |
| 5.6.2.3 | DNA 5'-3' helicase | DNA 5'-3' helicase (ATP-hydrolysing) | |
| 5.6.2.4 | DNA 3'-5' helicase | DNA 3'-5' helicase (ATP-hydrolysing) |
Proteins
| Protein ID | name | full name |
|---|---|---|
| O13768 | ptr8 | General transcription and DNA repair factor IIH helicase/translocase subunit XPB |
| O74880 | pcm1 | mRNA cap guanine-N(7) methyltransferase |
| P26659 | rad15 | General transcription and DNA repair factor IIH helicase subunit XPD |
| P40997 | ceg1 | mRNA-capping enzyme subunit alpha |
| Q12126 | crk1 | Serine/threonine-protein kinase crk1 |