Activation of NMDA receptors and postsynaptic events

Paoletti P, Bellone C, Zhou Q. NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease. Nat Rev Neurosci. 2013 Jun;14(6):383–400. doi: 10.1038/nrn3504. PMID: 23686171.; Hardingham GE, Bading H. Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nature Reviews Neuroscience. 2010 Sep 15;11(10):682–96. doi: 10.1038/nrn2911.; Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R. Glutamate Receptor Ion Channels: Structure, Regulation, and Function. Pharmacological Reviews. 2010 Sep;62(3):405–96. doi: 10.1124/pr.109.002451.; Cohen S, Greenberg ME. Communication Between the Synapse and the Nucleus in Neuronal Development, Plasticity, and Disease. Annu. Rev. Cell Dev. Biol. 2008 Nov 01;24(1):183–209. doi: 10.1146/annurev.cellbio.24.110707.175235.

Metabolites

3',5'-cyclic AMP(1-)

Formula: C10H11N5O6P (328.0446936)

CAS ID: 62906-31-4



Enzyme

EC Number name full name note
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)


Proteins

Protein ID name full name
P38070 YPK3 Serine/threonine-protein kinase YPK3