SMAC, XIAP-regulated apoptotic response

Saelens X, Festjens N, Vande Walle L, van Gurp M, van Loo G, Vandenabeele P. Toxic proteins released from mitochondria in cell death. Oncogene. 2004 Apr 12;23(16):2861–74. doi: 10.1038/sj.onc.1207523. PMID: 15077149.; Salvesen GS, Duckett CS. IAP proteins: blocking the road to death's door. Nature Reviews Molecular Cell Biology. 2002 Jun;3(6):401–10. doi: 10.1038/nrm830.

Metabolites



Enzyme

EC Number name full name note
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
3.4.22.56 caspase-3


Proteins

Protein ID name full name