Ub-specific processing proteases
Ye Y, Scheel H, Hofmann K, Komander D. Dissection of USP catalytic domains reveals five common insertion points. Mol Biosyst. 2009 Dec;5(12):1797–808. doi: 10.1039/b907669g. PMID: 19734957.; Reyes-Turcu FE, Wilkinson KD. Polyubiquitin binding and disassembly by deubiquitinating enzymes. Chem Rev. 2009 Apr;109(4):1495–508. PMID: 19243136; PMCID: PMC2734106.; Nijman SM, Luna-Vargas MP, Velds A, Brummelkamp TR, Dirac AM, Sixma TK, Bernards R. A genomic and functional inventory of deubiquitinating enzymes. Cell. 2005 Dec 02;123(5):773–86. doi: 10.1016/j.cell.2005.11.007. PMID: 16325574.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 4.2.99.- | |||
| 2.3.2.27 | RING-type E3 ubiquitin transferase | [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type) | |
| 2.7.11.25 | mitogen-activated protein kinase kinase kinase | ATP:protein phosphotransferase (MAPKKKK-activated) | |
| 2.7.7.7 | DNA-directed DNA polymerase | deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) | |
| 3.4.19.12 | ubiquitinyl hydrolase 1 | ||
| 3.6.4.12 | DNA helicase | ||
| 3.6.4.13 | RNA helicase | ||
| 4.2.99.18 | DNA-(apurinic or apyrimidinic site) lyase | DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase |
Proteins
| Protein ID | name | full name |
|---|