Recognition of DNA damage by PCNA-containing replication complex
Friedberg EC, Lehmann AR, Fuchs RP. Trading places: how do DNA polymerases switch during translesion DNA synthesis? Mol Cell. 2005 May 27;18(5):499–505. doi: 10.1016/j.molcel.2005.03.032. PMID: 15916957.; Hoege C, Pfander B, Moldovan GL, Pyrowolakis G, Jentsch S. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature. 2002 Sep 12;419(6903):135–41. doi: 10.1038/nature00991. PMID: 12226657.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 3.1.11.- | |||
| 2.3.2.23 | E2 ubiquitin-conjugating enzyme | S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:[E2 ubiquitin-conjugating enzyme] ubiquitinyl transferase | |
| 2.3.2.27 | RING-type E3 ubiquitin transferase | [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type) | |
| 2.3.2.32 | cullin-RING-type E3 NEDD8 transferase | [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine:[cullin] [NEDD8-protein] transferase (isopeptide bond-forming; RING-type) | |
| 2.7.7.7 | DNA-directed DNA polymerase | deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) | |
| 3.4.19.12 | ubiquitinyl hydrolase 1 |
Proteins
| Protein ID | name | full name |
|---|