Apoptotic cleavage of cellular proteins
Wee LJ, Tan TW, Ranganathan S. CASVM: web server for SVM-based prediction of caspase substrates cleavage sites. Bioinformatics. 2007 Dec 01;23(23):3241–3. doi: 10.1093/bioinformatics/btm334. PMID: 17599937.; Wee LJ, Tan TW, Ranganathan S. SVM-based prediction of caspase substrate cleavage sites. BMC Bioinformatics. 2006 Dec 18;7 Suppl 5():S14. PMID: 17254298; PMCID: PMC1764470.; Fischer U, Jänicke RU, Schulze-Osthoff K. Many cuts to ruin: a comprehensive update of caspase substrates. Cell Death & Differentiation. 2003 Jan;10(1):76–100. doi: 10.1038/sj.cdd.4401160.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.3.2.27 | RING-type E3 ubiquitin transferase | [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type) | |
| 2.5.1.58 | protein farnesyltransferase | farnesyl-diphosphate:protein-cysteine farnesyltransferase | |
| 2.5.1.59 | protein geranylgeranyltransferase type I | geranylgeranyl-diphosphate:protein-cysteine geranyltransferase | |
| 2.7.10.2 | non-specific protein-tyrosine kinase | ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) | |
| 2.7.11.1 | non-specific serine/threonine protein kinase | ATP:protein phosphotransferase (non-specific) | |
| 2.7.11.13 | protein kinase C | ATP:protein phosphotransferase (diacylglycerol-dependent) | |
| 2.7.11.39 | ROCK-subfamily protein kinase | ATP:cytoskeleton-protein phosphotransferase | |
| 3.4.22.56 | caspase-3 | ||
| 3.4.22.59 | caspase-6 | ||
| 3.4.22.60 | caspase-7 | ||
| 3.4.22.61 | caspase-8 |
Proteins
| Protein ID | name | full name |
|---|