APC/C:Cdc20 mediated degradation of mitotic proteins
Owens TJ, Hoyt MA. The D box asserts itself. Mol Cell. 2005 Jun 10;18(6):611–2. doi: 10.1016/j.molcel.2005.05.019. PMID: 15949434.; Zachariae W, Nasmyth K. Whose end is destruction: cell division and the anaphase-promoting complex. Genes Dev. 1999 Aug 15;13(16):2039–58. doi: 10.1101/gad.13.16.2039. PMID: 10465783.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.3.2.23 | E2 ubiquitin-conjugating enzyme | S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:[E2 ubiquitin-conjugating enzyme] ubiquitinyl transferase | |
| 2.7.11.1 | non-specific serine/threonine protein kinase | ATP:protein phosphotransferase (non-specific) |
Proteins
| Protein ID | name | full name |
|---|---|---|
| O00103 | ubc11 | Ubiquitin-conjugating enzyme E2-20 kDa |
| O13839 | fin1 | G2-specific protein kinase fin1 |
| O94751 | bub1 | Spindle assembly checkpoint serine/threonine-protein kinase bub1 |
| P46595 | ubc4 | Ubiquitin-conjugating enzyme E2 4 |
| Q9UTN8 | ubc14 | Ubiquitin-conjugating enzyme E2 14 |