L-cysteine biosynthesis III (from L-homocysteine)
Stipanuk MH. Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine. Annu Rev Nutr. 2004;24():539–77. doi: 10.1146/annurev.nutr.24.012003.132418. PMID: 15189131.; Finkelstein JD. Methionine metabolism in mammals. The Journal of Nutritional Biochemistry. 1990 May;1(5):228–37. doi: 10.1016/0955-2863(90)90070-2.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 4.2.1.22 | cystathionine beta-synthase | L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming) | |
| 4.4.1.1 | cystathionine gamma-lyase | L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming) | |
| 4.4.1.2 | homocysteine desulfhydrase | L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming) |
Proteins
| Protein ID | name | full name |
|---|