L-threonine degradation II

Dale RA. Catabolism of threonine in mammals by coupling of l-threonine 3-dehydrogenase with 2-amino-3-oxobutyrate-CoA ligase. Biochimica et Biophysica Acta (BBA) - General Subjects. 1978 Dec;544(3):496–503. doi: 10.1016/0304-4165(78)90324-0.; McGilvray D, Morris JG. Utilization of l-threonine by a species of Arthrobacter. A novel catabolic role for ‘aminoacetone synthase’. 1969 May 01;112(5):657–71. doi: 10.1042/bj1120657.

Metabolites

Beryllium

Formula: Be (9.012183)

CAS ID: 7440-41-7

Cadmium

Formula: Cd (113.903361)

CAS ID: 7440-43-9

Copper

Formula: Cu (62.929599)

CAS ID: 7440-50-8

Cyclohexane-1,2-dione

Formula: C6H8O2 (112.05242679999999)

CAS ID: 765-87-7

Diacetyl

Formula: C4H6O2 (86.0367776)

CAS ID: 431-03-8

Dithiothreitol

Formula: C4H10O2S2 (154.01222)

CAS ID: 3483-12-3

Fe2+

Formula: Fe (55.934939)

CAS ID: 15438-31-0

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

Manganese(2+)

Formula: Mn (54.938046)

CAS ID: 7439-96-5

Mercaptoethanol

Formula: C2H6OS (78.0139346)

CAS ID: 60-24-2

Mercury(2+)

Formula: Hg (201.970632)

CAS ID: 14302-87-5

Nickel(2+)

Formula: Ni (57.935347)

CAS ID: 14701-22-5

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

2,3-Pentanedione

Formula: C5H8O2 (100.05242679999999)

CAS ID: 600-14-6

Phenylglyoxal

Formula: C8H6O2 (134.0367776)

CAS ID: 1074-12-0

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

pyridoxal 5'-phosphate(2-)

Formula: C8H8NO6P (245.0089238)

CAS ID:

Dithionitrobenzoic acid

Formula: C14H6N2O8S2-2 (393.9565596)

CAS ID:



Enzyme

EC Number name full name note
1.1.1.1 alcohol dehydrogenase alcohol:NAD+ oxidoreductase
1.1.1.103 L-threonine 3-dehydrogenase L-threonine:NAD+ oxidoreductase
2.3.1.29 glycine C-acetyltransferase acetyl-CoA:glycine C-acetyltransferase


Proteins

Protein ID name full name
P07913 tdh L-threonine 3-dehydrogenase
P0AB77 kbl 2-amino-3-ketobutyrate coenzyme A ligase
P37686 yiaY Probable alcohol dehydrogenase