Dengue virus modulates apoptosis
Lu ZY, Cheng MH, Yu CY, Lin YS, Yeh TM, Chen CL, Chen CC, Wan SW, Chang CP. Dengue Nonstructural Protein 1 Maintains Autophagy through Retarding Caspase-Mediated Cleavage of Beclin-1. Int J Mol Sci. 2020 Dec 19;21(24). PMID: 33352639; PMCID: PMC7766445.; Amara A, Mercer J. Viral apoptotic mimicry. Nature Reviews Microbiology. 2015 Jun 08;13(8):461–9. doi: 10.1038/nrmicro3469.; Limonta D, Capó V, Torres G, Pérez AB, Guzmán MG. Apoptosis in tissues from fatal dengue shock syndrome. Journal of Clinical Virology. 2007 Sep;40(1):50–4. doi: 10.1016/j.jcv.2007.04.024.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.1.1.56 | mRNA (guanine-N7)-methyltransferase | S-adenosyl-L-methionine:mRNA (guanine-N7)-methyltransferase | |
| 2.1.1.57 | methyltransferase cap1 | S-adenosyl-L-methionine:5-(N7-methyl 5-triphosphoguanosine)-(ribonucleotide)-[mRNA] 2-O-methyltransferase | |
| 2.7.1.137 | phosphatidylinositol 3-kinase | ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase | |
| 2.7.10.2 | non-specific protein-tyrosine kinase | ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) | |
| 2.7.11.1 | non-specific serine/threonine protein kinase | ATP:protein phosphotransferase (non-specific) | |
| 2.7.7.48 | RNA-directed RNA polymerase | nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed) | |
| 3.4.21.91 | Flavivirin | ||
| 3.6.1.15 | nucleoside-triphosphate phosphatase | unspecific diphosphate phosphohydrolase | |
| 3.6.4.13 | RNA helicase |
Proteins
| Protein ID | name | full name |
|---|