SHOC2 M1731 mutant abolishes MRAS complex function
Hannig V, Jeoung M, Jang ER, Phillips JA, Galperin E. A Novel SHOC2 Variant in Rasopathy. Hum Mutat. 2014 Nov;35(11):1290–4. PMID: 25137548; PMCID: PMC4213265.; Rodriguez-Viciana P, Oses-Prieto J, Burlingame A, Fried M, McCormick F. A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity. Mol Cell. 2006 Apr 21;22(2):217–30. doi: 10.1016/j.molcel.2006.03.027. PMID: 16630891.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 3.6.5.2 | small monomeric GTPase | GTP phosphohydrolase (cell-regulating) |
Proteins
| Protein ID | name | full name |
|---|