RAC2 GTPase cycle

Lougaris V, Baronio M, Gazzurelli L, Benvenuto A, Plebani A. RAC2 and primary human immune deficiencies. J Leukoc Biol. 2020 Aug;108(2):687–96. doi: 10.1002/jlb.5mr0520-194rr. PMID: 32542921.; Troeger A, Williams DA. Hematopoietic-specific Rho GTPases Rac2 and RhoH and human blood disorders. Experimental Cell Research. 2013 Sep;319(15):2375–83. doi: 10.1016/j.yexcr.2013.07.002.; Gu Y, Williams DA. RAC2 GTPase Deficiency and Myeloid Cell Dysfunction in Human and Mouse. Journal of Pediatric Hematology/Oncology. 2002 Dec;24(9):791–4. doi: 10.1097/00043426-200212000-00027.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2



Enzyme

EC Number name full name note
1.6.3.-
3.6.5.2 small monomeric GTPase GTP phosphohydrolase (cell-regulating)


Proteins

Protein ID name full name