Mitochondrial transcription initiation

Fernández-Silva P, Enriquez JA, Montoya J. Replication and transcription of mammalian mitochondrial DNA. Exp Physiol. 2003 Jan;88(1):41–56. doi: 10.1113/eph8802514. PMID: 12525854.; Seidel-Rogol BL, McCulloch V, Shadel GS. Human mitochondrial transcription factor B1 methylates ribosomal RNA at a conserved stem-loop. Nat Genet. 2003 Jan;33(1):23–4. doi: 10.1038/ng1064. PMID: 12496758.; Falkenberg M, Gaspari M, Rantanen A, Trifunovic A, Larsson NG, Gustafsson CM. Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA. Nat Genet. 2002 Jul;31(3):289–94. doi: 10.1038/ng909. PMID: 12068295.; McCulloch V, Seidel-Rogol BL, Shadel GS. A Human Mitochondrial Transcription Factor Is Related to RNA Adenine Methyltransferases and Binds S-Adenosylmethionine. Molecular and Cellular Biology. 2002 Feb 01;22(4):1116–25. doi: 10.1128/mcb.22.4.1116-1125.2002.; Clayton DA. Transcription and replication of mitochondrial DNA. Hum Reprod. 2000 Jul;15 Suppl 2():11–7. doi: 10.1093/humrep/15.suppl_2.11. PMID: 11041509.

Metabolites



Enzyme

EC Number name full name note
2.1.1.-
2.7.7.6 DNA-directed RNA polymerase nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed)


Proteins

Protein ID name full name
O13993 rpo41 DNA-directed RNA polymerase, mitochondrial
Q9US51 mtf1 Mitochondrial transcription factor 1