linifanib-resistant FLT3 mutants
Nguyen B, Williams AB, Young DJ, Ma H, Li L, Levis M, Brown P, Small D. FLT3 activating mutations display differential sensitivity to multiple tyrosine kinase inhibitors. Oncotarget. 2017 Feb 14;8(7):10931–44. PMID: 28077790; PMCID: PMC5355235.; Hernandez-Davies JE, Zape JP, Landaw EM, Tan X, Presnell A, Griffith D, Heinrich MC, Glaser KB, Sakamoto KM. The multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3ß-dependent pathway. Mol Cancer Ther. 2011 Jun;10(6):949–59. PMID: 21471285; PMCID: PMC3112478.