Gastrulation

Rossant J, Tam PPL. Early human embryonic development: Blastocyst formation to gastrulation. Dev Cell. 2022 Jan 24;57(2):152–65. doi: 10.1016/j.devcel.2021.12.022. PMID: 35077679.; Zhai J, Xiao Z, Wang Y, Wang H. Human embryonic development: from peri-implantation to gastrulation. Trends Cell Biol. 2022 Jan;32(1):18–29. doi: 10.1016/j.tcb.2021.07.008. PMID: 34417090.; Amack JD. Cellular dynamics of EMT: lessons from live in vivo imaging of embryonic development. Cell Communication and Signaling. 2021 Jul 22;19(1):79. doi: 10.1186/s12964-021-00761-8.; Scheibner K, Schirge S, Burtscher I, Büttner M, Sterr M, Yang D, Böttcher A, Ansarullah, Irmler M, Beckers J, Cernilogar FM, Schotta G, Theis FJ, Lickert H. Epithelial cell plasticity drives endoderm formation during gastrulation. Nature Cell Biology. 2021 Jun 24;23(7):692–703. doi: 10.1038/s41556-021-00694-x.; Ghimire S, Mantziou V, Moris N, Martinez Arias A. Human gastrulation: The embryo and its models. Dev Biol. 2021 Jun;474():100–8. doi: 10.1016/j.ydbio.2021.01.006. PMID: 33484705.; Probst S, Sagar, Tosic J, Schwan C, Grün D, Arnold SJ. Spatiotemporal sequence of mesoderm and endoderm lineage segregation during mouse gastrulation. Development. 2021 Jan 07;148(1). doi: 10.1242/dev.193789. PMID: 33199445.; Bardot ES, Hadjantonakis A. Mouse gastrulation: Coordination of tissue patterning, specification and diversification of cell fate. Mechanisms of Development. 2020 Sep;163():103617. doi: 10.1016/j.mod.2020.103617.; Kojima Y, Tam OH, Tam PPL. Timing of developmental events in the early mouse embryo. Seminars in Cell & Developmental Biology. 2014 Oct;34():65–75. doi: 10.1016/j.semcdb.2014.06.010.; Technau U, Scholz CB. Origin and evolution of endoderm and mesoderm. Int. J. Dev. Biol. 2003;47(7-8):531–9. doi: 10.1387/ijdb.14756329.

Metabolites

Retinoate

Formula: C20H28O2 (300.2089188)

CAS ID: 302-79-4



Enzyme

EC Number name full name note
2.3.1.-
2.3.1.48 histone acetyltransferase acetyl-CoA:[protein]-L-lysine acetyltransferase
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
2.4.1.222 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase UDP-N-acetyl-alpha-D-glucosamine:[protein with EGF-like domain]-3-O-(alpha-L-fucosyl)-(L-serine/L-threonine) 3-beta-N-acetyl-D-glucosaminyltransferase (configuration-inverting)
2.7.10.1 receptor protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type)


Proteins

Protein ID name full name