protein S-nitrosylation and denitrosylation

Hess DT, Matsumoto A, Kim S, Marshall HE, Stamler JS. Protein S-nitrosylation: purview and parameters. Nature Reviews Molecular Cell Biology. 2005 Feb 01;6(2):150–66. doi: 10.1038/nrm1569.; Liu L, Hausladen A, Zeng M, Que L, Heitman J, Stamler JS. A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans. Nature. 2001 Mar 22;410(6827):490–4. doi: 10.1038/35068596. PMID: 11260719.; Jensen DE, Belka GK, Du Bois GC. S-Nitrosoglutathione is a substrate for rat alcohol dehydrogenase class III isoenzyme. Biochem J. 1998 Apr 15;331 ( Pt 2)():659–68. PMID: 9531510; PMCID: PMC1219401.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydroxylamine

Formula: NH3O (33.0214628)

CAS ID: 7803-49-8

Nitric oxide

Formula: NO (29.997989)

CAS ID: 10102-43-9

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Superoxide

Formula: O2 (31.98983)

CAS ID: 11062-77-4

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

S-nitrosoglutathione(1-)

Formula: C10H15N4O7S (335.066142)

CAS ID:



Enzyme

EC Number name full name note
1.1.1.-
1.1.1.1 alcohol dehydrogenase alcohol:NAD+ oxidoreductase
1.1.1.284 S-(hydroxymethyl)glutathione dehydrogenase S-(hydroxymethyl)glutathione:NAD+ oxidoreductase


Proteins

Protein ID name full name
P32771 SFA1 S-(hydroxymethyl)glutathione dehydrogenase