melatonin degradation II

Hardeland R. Melatonin, hormone of darkness and more – occurrence, control mechanisms, actions and bioactive metabolites. Cellular and Molecular Life Sciences. 2008 Mar 17;65(13):2001–18. doi: 10.1007/s00018-008-8001-x.; Slominski A, Tobin DJ, Zmijewski MA, Wortsman J, Paus R. Melatonin in the skin: synthesis, metabolism and functions. Trends Endocrinol Metab. 2008 Jan;19(1):17–24. doi: 10.1016/j.tem.2007.10.007. PMID: 18155917.; Grace MS, Besharse JC. Melatonin deacetylase activity in the pineal gland and brain of the lizards Anolis carolinensis and Sceloporus jarrovi. Neuroscience. 1994 Sep;62(2):615–23. doi: 10.1016/0306-4522(94)90393-x. PMID: 7530349.; Grace MS, Cahill GM, Besharse JC. Melatonin deacetylation: retinal vertebrate class distribution and Xenopus laevis tissue distribution. Brain Res. 1991 Sep 13;559(1):56–63. doi: 10.1016/0006-8993(91)90286-5. PMID: 1782560.

Metabolites

5-Methoxyindoleacetate

Formula: C11H11NO3 (205.0738896)

CAS ID: 3471-31-6

5-Methoxytryptamine

Formula: C11H14N2O (190.1106074)

CAS ID: 608-07-1

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydrogen peroxide

Formula: H2O2 (34.0054792)

CAS ID: 7722-84-1

Melatonin

Formula: C13H16N2O2 (232.1211716)

CAS ID: 73-31-4

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

5-Methoxyindoleacetaldehyde

Formula: C11H11NO2 (189.0789746)

CAS ID: 22139-72-6

acetate

Formula: C2H3O2 (59.0133038)

CAS ID: 71-50-1



Enzyme

EC Number name full name note
1.4.3.21 primary-amine oxidase primary-amine:oxygen oxidoreductase (deaminating)
1.4.3.4 monoamine oxidase amine:oxygen oxidoreductase (deaminating)


Proteins

Protein ID name full name