traumatin and (Z)-3-hexen-1-yl acetate biosynthesis

Yamauchi Y, Hasegawa A, Taninaka A, Mizutani M, Sugimoto Y. NADPH-dependent Reductases Involved in the Detoxification of Reactive Carbonyls in Plants. Journal of Biological Chemistry. 2011 Mar;286(9):6999–7009. doi: 10.1074/jbc.m110.202226.; Noordermeer MA, Veldink GA, Vliegenthart JF. Fatty acid hydroperoxide lyase: a plant cytochrome p450 enzyme involved in wound healing and pest resistance. Chembiochem. 2001 Aug 03;2(7-8):494–504. doi: 10.1002/1439-7633(20010803)2:7/8<494::aid-cbic494>3.0.co;2-1. PMID: 11828481.; Bate NJ, Sivasankar S, Moxon C, Riley JM, Thompson JE, Rothstein SJ. Molecular characterization of an Arabidopsis gene encoding hydroperoxide lyase, a cytochrome P-450 that is wound inducible. Plant Physiol. 1998 Aug;117(4):1393–400. PMID: 9701595; PMCID: PMC34903.; Bell E, Creelman RA, Mullet JE. A chloroplast lipoxygenase is required for wound-induced jasmonic acid accumulation in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A. 1995 Sep 12;92(19):8675–9. doi: 10.1073/pnas.92.19.8675.; Seitz G, Klein W. [The reactivity of dimethyl croconate towards methylene active species (author's transl)]. Arch Pharm (Weinheim). 1975 Dec;308(12):960–3. doi: 10.1002/ardp.19753081211. PMID: 1221977.; Christopher J, Pistorius E, Axelrod B. Isolation of an isozyme of soybean lipoxygenase. Biochimica et Biophysica Acta (BBA) - Enzymology. 1970 Jan;198(1):12–9. doi: 10.1016/0005-2744(70)90028-8.; Theorell H, Holman RT, Åkeson Å, Linnasalmi A, Laukkanen P. Crystalline Lipoxidase. Acta Chem. Scand. 1947;1():571–6. doi: 10.3891/acta.chem.scand.01-0571.

Metabolites

(E)-2-Hexenal

Formula: C6H10O (98.07316100000001)

CAS ID: 6728-26-3

3-Hexenal

Formula: C6H10O (98.07316100000001)

CAS ID: 6789-80-6

3-Hexenol

Formula: C6H12O (100.0888102)

CAS ID: 928-96-1

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

2-Hexen-1-ol

Formula: C6H12O (100.0888102)

CAS ID: 928-95-0

linoleate

Formula: C18H31O2 (279.23239259999997)

CAS ID: 1509-85-9

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.1.1.-
1.1.1.208 (+)-neomenthol dehydrogenase (+)-neomenthol:NADP+ oxidoreductase
1.13.11.12 linoleate 13S-lipoxygenase linoleate:oxygen 13-oxidoreductase
2.3.1.195 (Z)-3-hexen-1-ol acetyltransferase acetyl-CoA:(3Z)-hex-3-en-ol acetyltransferase


Proteins

Protein ID name full name