Vinylacetylglycine (BioCAD00000019857)

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Metabolite Card

Formula: C6H9NO3 (143.0582)
SMILES: OC(=O)CNC(=O)CC=C

Synonyms [en]

Vinylacetylglycine; 2-(But-3-enamido)acetic acid; N-but-3-enoylglycine; (but-3-enoylamino)acetic acid; N-vinylacetylglycine; 2-(but-3-enoylamino)acetic acid

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Vinylacetylglycine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000019857). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Vinylacetylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:. acyl-CoA + glycine < -- > CoA + N-acylglycine. Vinylacetylglycine is a human metabolite that had been identified in a GC/MS urine screen. Increased amounts of this metabolite in the urine has been linked to a metabolomic disorder termed Isovaleric acidemia. (Gas-Chromatographic Method of Analysis for Urinary Organic Acids. I. Retention indices of 155 metaboically Important Compounds; Kay Tanaka, David G. Hine, Agnes West-Dull, and Theodore B. Lynn.).

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 73122-61-9
  • PubChem: 53477718
  • ChEBI: ChEBI:74435
  • HMDB: HMDB0000894
  • HMDB: HMDB00894
  • RefMet: RM0136019
  • MoNA: HMDB0000894_ms_ms_1259
  • MoNA: HMDB0000894_ms_ms_1260
  • MoNA: HMDB0000894_ms_ms_1261
  • Metlin: METLIN_5851
  • Coconut NaturalProduct: CNP0002379.0

Class / Ontology

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Pathway Synthetic

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