Phenolphthalein (BioCAD00000016143)
Metabolite Card
Formula: C20H14O4 (318.0892)
SMILES: OC1=CC=C(C=C1)C1(OC(=O)C2=CC=CC=C12)C1=CC=C(O)C=C1
Synonyms [en]
phenolphthalein; 3,3-Bis(4-hydroxyphenyl)phthalide; Phthalin; Euchessina; Phthalimetten; IDI1_000929
Last reviewed on 2024-06-28.
Cite this Page
Phenolphthalein. 数据之源,洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000016143). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Phenolphthalein appears as white or yellowish-white to pale orange fine crystalline powder. Odorless. Aqueous solution is acidic. Colorless to pH 8.5; pink to deep-red above pH 9. Colorless in presence of large amounts of alkali. Tasteless. (NTP, 1992) Phenolphthalein is a member of phenols. It is functionally related to a 2-benzofuran-1(3H)-one. Phenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997. Phenolphthalein is a natural product found in Caragana conferta with data available. Phenolphthalein is an organic compound used as a laboratory reagent and pH indicator. Phenolphthalein exerts laxative effects by stimulating the intestinal mucosa and constricting smooth muscles. However, phenolphthalein is no longer used as a laxative due to the suspected carcinogenicity of this compound. Phenolphthalein can cause cancer according to The Food and Drug Administration (FDA) and The National Toxicology Program. Phenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997. An acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic.
DBLinks
- CAS Registry Number: 77-09-8
- PubChem CID: 4764
- ChEBI: 34914
- HMDB: HMDB0256412
- LipidMaps:
- KEGG: C14286
- BioCyc:
- NCBI MeSH: Phenolphthalein
- Wikipedia: Phenolphthalein
Other DBLinks
- CAS Registry Number: 5768-87-6
- CAS Registry Number: 77-09-8
- PubChem: 4764
- ChEBI: ChEBI:34914
- HMDB: HMDB0256412
- KEGG: C14286
- KEGG: D05456
- NCBI MeSH: Phenolphthalein
- Wikipedia: Phenolphthalein
- DrugBank: DB04824
- RefMet: RM0200205
- MoNA: LU017301
- MoNA: LU017302
- MoNA: LU017303
- MoNA: LU017304
- MoNA: LU017305
- MoNA: LU017306
- MoNA: LU017351
- MoNA: LU017352
- MoNA: LU017353
- MoNA: LU017354
- MoNA: LU017355
- MoNA: LU017356
- Metlin: METLIN_44257
- Coconut NaturalProduct: CNP0268135.0
Class / Ontology
- WishartLab ClassyFire: [Benzofuranones] Benzofuranones
- RefMet: [Benzofurans] Benzofurans
- ChEBI: [CHEBI:34914] phenolphthalein