D-Ornithine (BioCAD00000009420)
blood feces saliva epidermis fibroblasts intestine liver placenta skeletal muscle spleen plant natural products
Metabolite Card
Formula: C5H12N2O2 (132.0899)
SMILES: NCCC[C@@H](N)C(O)=O
Synonyms [en]
D-Ornithine; (R)-Ornithine; (2R)-2,5-Diaminopentanoic acid; Ornithine; 2H368YCK0U; D-Ornitrine
Last reviewed on 2024-06-28.
Cite this Page
D-Ornithine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000009420). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
D-Ornithine is an amino acid produced in the urea cycle by the splitting off of urea from arginine. Ornithine is one of the products of the action of the enzyme arginase on L-arginine, creating urea. Therefore, ornithine is a central part of the urea cycle, which allows for the disposal of excess nitrogen. D-Ornithine has been identified in the human placenta (PMID: 32033212).
DBLinks
- CAS Registry Number: 348-66-3
- PubChem CID: 71082
- ChEBI: 16176
- HMDB: HMDB0003374
- LipidMaps:
- KEGG: C00515
- BioCyc: CPD-217
- NCBI MeSH:
- Wikipedia: Ornithine
Other DBLinks
- CAS Registry Number: 16682-12-5
- CAS Registry Number: 348-66-3
- PubChem: 71082
- ChEBI: ChEBI:16176
- HMDB: HMDB0003374
- HMDB: HMDB03374
- KEGG: C00515
- BioCyc: CPD-217
- Wikipedia: Ornithine
- RefMet: RM0136216
- MoNA: BAF_UVA_POS001294
- MoNA: BAF_UVA_POS001440
- MoNA: BAF_UVA_POS001441
- MoNA: BAF_UVA_POS001442
- MoNA: BAF_UVA_POS001443
- MoNA: CCMSLIB00000577961
- MoNA: CCMSLIB00000578195
- MoNA: CCMSLIB00005720399
- MoNA: CCMSLIB00005720692
- MoNA: EMBL-MCF_spec115245
- MoNA: EMBL-MCF_spec43851
- MoNA: KO003637
- MoNA: KO003638
- MoNA: KO003639
- MoNA: KO003640
- MoNA: KO003641
- MoNA: MoNA001824
- MoNA: MoNA001825
- MoNA: MoNA001827
- MoNA: MoNA024159
- Metlin: METLIN_6910
- Coconut NaturalProduct: CNP0102727.2
Class / Ontology
- WishartLab ClassyFire: [Amino acids, peptides, and analogues] Amino acids, peptides, and analogues
- RefMet: [Amino acids] Amino acids
- ChEBI: [CHEBI:16176] D-ornithine
- Coconut NaturalProduct: [Aminoacids] Aminoacids
| ID | EC Number | Name |
|---|---|---|
| KEGG:R00672 | 5.1.1.9 | ornithine racemase |
| KEGG:R02457 | 1.4.3.3 | D-ornithine:oxygen oxidoreductase (deaminating) |
| KEGG:R02458 | 3.5.3.10 | D-arginine amidinohydrolase |
| KEGG:R02459 | 2.6.1.21 | D-ornithine:2-oxoglutarate aminotransferase |
| KEGG:R02460 | bacitracin synthetase 2 | |
| KEGG:R02461 | 5.4.3.5 | D-ornithine 4,5-aminomutase |
| KEGG:R12304 | 4.1.1.116 | D-ornithine carboxy-lyase |
| KEGG:R12353 | 6.3.2.58 | D-ornithine:citrate ligase (AMP-forming) |
| BioCyc:ORNMUTST-RXN | 5.4.3.5 | CPD-217<=>24DINH2-PENTANOATE |
| BioCyc:RXN-13083 | 6.3.2.59 | CPD-217 + LYS + ATP --> CPD-14097 + ADP + Pi + PROTON |
| BioCyc:RXN-20175 | 4.1.1.116 | CPD-217 + PROTON --> PUTRESCINE + CARBON-DIOXIDE |
| BioCyc:ORNITHINE-RACEMASE-RXN | 5.1.1.12 | L-ORNITHINE<=>CPD-217 |
| BioCyc:D-ARGINASE-RXN | 3.5.3.10 | WATER + CPD-220<=>UREA + CPD-217 |
| BioCyc:RXN-19522 | 6.3.2.58 | CPD-217 + CIT + ATP --> CPD-21047 + AMP + PPI + PROTON |
Taxonomy Source
- Allium sativum [ncbi taxid: 4682]
- Angelica acutiloba [ncbi taxid: 55605]
- Angelica gigas [ncbi taxid: 85712]
- Angelica sinensis [ncbi taxid: 165353]
- Homo sapiens [ncbi taxid: 9606]
- Lycium barbarum [ncbi taxid: 112863]
- Lycium chinense [ncbi taxid: 112883]
- Mus musculus [ncbi taxid: 10090]
Pathway Synthetic
| pathway id | name |
|---|---|
| WikiPathways:WP4657 | 22q11.2 copy number variation syndrome |
| WikiPathways:WP1642 | D-arginine and D-ornithine metabolism |
| PathBank:SMP0087378 | D-Arginine and D-Ornithine Metabolism |
| PathBank:SMP0063608 | D-Arginine and D-Ornithine Metabolism |
| PathBank:SMP0087433 | D-Arginine and D-Ornithine Metabolism |
| PathBank:SMP0000036 | D-Arginine and D-Ornithine Metabolism |
| PathBank:SMP0087190 | D-Arginine and D-Ornithine Metabolism |
| PathBank:SMP0087291 | D-Arginine and D-Ornithine Metabolism |