NAD(P)+ (BioCAD00000762620)

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Metabolite Card

Formula: ()
SMILES: C5(/C=C\C(\C(=O)N)=C/[N+](/[C@@H]1(O[C@@H]([C@H]([C@H]1O)O)COP(OP(OC[C@H]4(O[C@@H](N2(C3(\C(\N=C/2)=C(N)/N=C\N=3)))[C@H](O[R])[C@H](O)4))(=O)[O-])(=O)[O-]))=5)

Synonyms [en]

NAD(P)+; β-NAD(P)+; NAD(P)+; NAD(P)

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

NAD(P)+. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000762620). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

|FRAME: NAD-P-OR-NOP| is a class of compounds including the instances |FRAME: NAD| and |FRAME: NADP|.|FRAME: NAD| and |FRAME: NADP| are dinucleotides containing one |FRAME: NIACINAMIDE| base and one |FRAME: ADENINE| base. Each nucleotide is connected to a ribose sugar at position 1, and the two riboses are connected at their 5 position via a diphosphate. The only difference between the two is that in NADP there is an additional phosphate group at the 2' position of the ribose that carries the adenine moiety.These molecules are biological carriers of reductive equivalents (i.e. high potential electrons). They are often referred to as coenzymes, although in most of their reactions they function as cosubstrates rather than true coenzymes.The most common function of |FRAME: NAD| is to accept two electrons and a proton (a hydride ion) from a substrate that is being oxidized. This reduction converts |FRAME: NAD| to |FRAME: NADH|, the reduced form. NADH then diffuses or is transported to a terminal oxidase, where the electrons are passed on, regenerating the oxidized form.|FRAME: NADPH|, on the other hand, is mostly involved in biosynthetic reactions, where it serves as an electron donor. NADPH is formed by reduction of |FRAME: NADP|, which occurs by different mechanisms in different types of organisms. In photosynthetic organisms |FRAME: NADP| is reduced by |FRAME: CPLX-84|. In heterotrophic organisms it is reduced by central metabolism processes such as the pentose phosphate pathway (see |FRAME: OXIDATIVEPENT-PWY|).

Entity Information

DBLinks

  • CAS Registry Number:
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  • KEGG:
  • BioCyc: NAD-P-OR-NOP
  • NCBI MeSH:
  • Wikipedia:
Other DBLinks
  • BioCyc: NAD-P-OR-NOP

Class / Ontology

Metabolic Network
ID EC Number Name
BioCyc:1.1.1.264-RXN 1.1.1.264 L-IDONATE + NAD-P-OR-NOP<=>5-DEHYDROGLUCONATE + NADH-P-OR-NOP + PROTON
BioCyc:1.5.1.20-RXN 1.5.1.20 METHYLENE-THF-GLU-N + NADH-P-OR-NOP + PROTON --> 5-METHYL-THF-GLU-N + NAD-P-OR-NOP
BioCyc:GLYC3PDEHYDROGBIOSYN-RXN 1.1.1.94 GLYCEROL-3P + NAD-P-OR-NOP<=>DIHYDROXY-ACETONE-PHOSPHATE + NADH-P-OR-NOP + PROTON
BioCyc:PYRROLINECARBREDUCT-RXN 1.5.1.2 L-DELTA1-PYRROLINE_5-CARBOXYLATE + NADH-P-OR-NOP + 2 PROTON --> PRO + NAD-P-OR-NOP
BioCyc:RXN66-546 1.5.1.2 NADH-P-OR-NOP + PYRROLINE-HYDROXY-CARBOXYLATE + 2 PROTON --> 4-HYDROXY-L-PROLINE + NAD-P-OR-NOP
BioCyc:RXN-14014 1.17.1.8 CPD-14443 + NADH-P-OR-NOP + PROTON --> DELTA1-PIPERIDEINE-2-6-DICARBOXYLATE + NAD-P-OR-NOP + WATER
BioCyc:HOMOSERDEHYDROG-RXN 1.1.1.3 L-ASPARTATE-SEMIALDEHYDE + NADH-P-OR-NOP + PROTON --> HOMO-SER + NAD-P-OR-NOP
BioCyc:GLUCONATE-5-DEHYDROGENASE-RXN 1.1.1.69 GLUCONATE + NAD-P-OR-NOP<=>5-DEHYDROGLUCONATE + NADH-P-OR-NOP + PROTON
BioCyc:RXN-10745 1.6.3.1 NADH-P-OR-NOP + PROTON + OXYGEN-MOLECULE --> NAD-P-OR-NOP + HYDROGEN-PEROXIDE
BioCyc:RXN-5921 1.14.13.239 CARNITINE + OXYGEN-MOLECULE + NADH-P-OR-NOP + PROTON --> CPD-16618 + TRIMETHYLAMINE + NAD-P-OR-NOP + WATER
BioCyc:R621-RXN 1.14.12.17 NADH-P-OR-NOP + 2 NITRIC-OXIDE + 2 OXYGEN-MOLECULE --> NAD-P-OR-NOP + 2 NITRATE + PROTON
BioCyc:RXN-13853 1.7.1.- Nitroaromatic-Compounds + 2 NADH-P-OR-NOP + 2 PROTON --> Hydroxylaminoaromatic-Compounds + 2 NAD-P-OR-NOP + WATER
BioCyc:R165-RXN 1.1.1.154 NAD-P-OR-NOP + CPD-1091 --> NADH-P-OR-NOP + CPD-389 + PROTON
BioCyc:RXN-18258 1.14.13.239 GAMMA-BUTYROBETAINE + OXYGEN-MOLECULE + NADH-P-OR-NOP + PROTON --> SUCC-S-ALD + TRIMETHYLAMINE + NAD-P-OR-NOP + WATER
BioCyc:RXN-7632 1.1.1.237 34-DIHYDROXYPHENYLPYRUVATE + NADH-P-OR-NOP + PROTON --> CPD-6982 + NAD-P-OR-NOP
BioCyc:FMN-RED-RXN NADH-P-OR-NOP + Ox-FMN-Flavoproteins + 2 PROTON --> NAD-P-OR-NOP + Red-FMNH2-Flavoproteins
BioCyc:RXN0-3381 CR+6 + 2 NADH-P-OR-NOP + OXYGEN-MOLECULE --> CR+3 + 2 NAD-P-OR-NOP + SUPER-OXIDE + 2 PROTON
BioCyc:RXN-16333 NAD-P-OR-NOP + PROTON + 2 E- --> NADH-P-OR-NOP
BioCyc:FMNREDUCT-RXN 1.5.1.39 NADH-P-OR-NOP + FMN + 2 PROTON --> NAD-P-OR-NOP + FMNH2
BioCyc:RXN-10745-1 1.6.3.- 2 NADH-P-OR-NOP + 3 OXYGEN-MOLECULE --> 2 NAD-P-OR-NOP + HYDROGEN-PEROXIDE + 2 SUPER-OXIDE
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Organism Source

Taxonomy Source

Pathway Synthetic

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