Biocytin (BioCAD00000007464)

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Metabolite Card

Formula: C16H28N4O4S (372.1831)
SMILES: [H][C@]12CS[C@@H](CCCCC(=O)NCCCC[C@H](N)C(O)=O)[C@@]1([H])NC(=O)N2

Synonyms [en]

biocytin; epsilon-N-Biotinyl-L-lysine; N(epsilon)-biotinyl-L-lysine; N6-D-Biotinyl-L-lysine; N(6)-D-biotinyl-L-lysine; N-biotinyl-L-lysine

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Biocytin. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000007464). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Biocytin is a naturally occurring low molecular weight analog of biotin, and a primary source of this essential metabolite for mammals. Biotinidase acts as a hydrolase by cleaving biocytin and biotinyl-peptides, thereby liberating biotin for reutilization. Mammals cannot synthesize biotin and, therefore, derive the vitamin from dietary sources or from the endogenous turnover of the carboxylases. Free biotin can readily enter the biotin pool, whereas holocarboxylases or other biotin-containing proteins must first be degraded proteolytically to biocytin (biotinyl-e-lysine) or biotinyl-peptides. Biocytin is also an especially versatile marker for neuroanatomical investigations, shown that may have multiple applications, especially for labeling neurons. (PMID:8930409, 1384763, 2479450).

Extracellular Mitochondria Nucleus
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 576-19-2
  • PubChem: 83814
  • ChEBI: ChEBI:27870
  • HMDB: HMDB0003134
  • KEGG: C05552
  • NCBI MeSH: biocytin
  • Wikipedia: Biocytin
  • RefMet: RM0158825
  • MoNA: HMDB0003134_ms_ms_2200
  • MoNA: HMDB0003134_ms_ms_2201
  • MoNA: HMDB0003134_ms_ms_2202
  • Metlin: METLIN_3509
  • Coconut NaturalProduct: CNP0307487.1

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R01077 3.5.1.12 N6-D-biotinyl-L-lysine amidohydrolase
KEGG:R04869 3.4.-.- C05552 + 2 C00012<=>C06250 + 2 C00001
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
WikiPathways:WP5355 Metabolic Epileptic Disorders
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