Aristolochic acid (BioCAD00000006785)

blood plant natural products

Metabolite Card

Formula: C17H11NO7 (341.0535)
SMILES: COC1=CC=CC2=C3C4=C(OCO4)C=C(C(O)=O)C3=C(C=C12)N(=O)=O

Synonyms [en]

aristolochic acid; aristolochic acid I; Aristolochin; aristolochic acid A; Aristolochic acid-I; Tardolyt

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Aristolochic acid. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000006785). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic." []

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 313-67-7
  • PubChem: 2236
  • ChEBI: ChEBI:2825
  • HMDB: HMDB0248598
  • KEGG: C08469
  • NCBI MeSH: aristolochic acid I
  • Wikipedia: Aristolochic_acid
  • RefMet: RM0046445
  • Metlin: METLIN_44093
  • Coconut NaturalProduct: CNP0490967.0
  • Coconut NaturalProduct: CNP0520464.0

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

  1. Akebia quinata [ncbi taxid: 13331]
  2. Akebia trifoliata [ncbi taxid: 155132]
  3. Amomum giganteum [ncbi taxid: ]
  4. Aristolochia [ncbi taxid: 12947]
  5. Aristolochia argentina [ncbi taxid: 158534]
  6. Aristolochia cinnabarina [ncbi taxid: ]
  7. Aristolochia cinnarbarina [ncbi taxid: ]
  8. Aristolochia clematis [ncbi taxid: ]
  9. Aristolochia clematitis L. [ncbi taxid: ]
  10. Aristolochia constricta [ncbi taxid: ]
  11. Aristolochia contorta [ncbi taxid: 266420]
  12. Aristolochia debilis [ncbi taxid: 158541]
  13. Aristolochia elegans [ncbi taxid: 143780]
  14. Aristolochia fangchi [ncbi taxid: 425107]
  15. Aristolochia foveolata [ncbi taxid: 158544]
  16. Aristolochia heterophylla [ncbi taxid: 431268]
  17. Aristolochia heterophylla Hemsl [ncbi taxid: ]
  18. Aristolochia indica [ncbi taxid: 158548]
  19. Aristolochia kaempferi [ncbi taxid: 158550]
  20. Aristolochia kunmingensis [ncbi taxid: 1907485]
  21. Aristolochia longa [ncbi taxid: ]
  22. Aristolochia manchuriensis [ncbi taxid: ]
  23. Aristolochia manshuriensis [ncbi taxid: 158555]
  24. Aristolochia maurorum [ncbi taxid: 158556]
  25. Aristolochia mollissima [ncbi taxid: 158558]
  26. Aristolochia moupinensis [ncbi taxid: 158559]
  27. Aristolochia ponticum [ncbi taxid: ]
  28. Aristolochia pubescens [ncbi taxid: ]
  29. Aristolochia rotunda [ncbi taxid: 360044]
  30. Aristolochia rotunda L. [ncbi taxid: ]
  31. Aristolochia sp. [ncbi taxid: ]
  32. Aristolochia tuberosa [ncbi taxid: 1523941]
  33. Aristolochia tubiflora [ncbi taxid: 1541216]
  34. Asarum canadense [ncbi taxid: 28498]
  35. Asarum heterotropoides [ncbi taxid: 366663]
  36. Asarum sieboldii [ncbi taxid: 76098]
  37. Asiasarum heterotropoides [ncbi taxid: ]
  38. Asiasarum sieboldii [ncbi taxid: ]
  39. Chondria atropurpurea [ncbi taxid: 1497626]
  40. Coffea canephora [ncbi taxid: 49390]
  41. Couepia polyandra [ncbi taxid: 1856781]
  42. Dimerostemma asperatum [ncbi taxid: 244147]
  43. Dioscorea collettii var. hypoglauca [ncbi taxid: 357960]
  44. Dysophylla verticillata [ncbi taxid: ]
  45. Erysimum rhaeticum [ncbi taxid: 761866]
  46. Ficus cordata [ncbi taxid: 309266]
  47. Lavandula hybrida [ncbi taxid: ]
  48. Manihot esculenta [ncbi taxid: 3983]
  49. Mizuhopecten yessoensis [ncbi taxid: 6573]
  50. Nerium oleander [ncbi taxid: 63479]
  51. Papaver nudicaule [ncbi taxid: 74823]
  52. Rumex alpinus [ncbi taxid: 1351827]
  53. Sinomenium acutum [ncbi taxid: 152363]
  54. Spatoglossum schmittii [ncbi taxid: ]
  55. Stephania tetrandra [ncbi taxid: 425106]
  56. Aristolochia auricularia [ncbi taxid: ]
  57. Aristolochia cinnabarina [ncbi taxid: ]

Pathway Synthetic

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