Angiotensin III (BioCAD00000006590)

blood

Metabolite Card

Formula: C46H66N12O9 (930.5075)
SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCN=C(N)N)C(C)C)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

Synonyms [en]

ANGIOTENSIN III; Des-Asp-1-Angiotensin II; (2S)-2-{[(2S)-1-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-[(diaminomethylidene)amino]pentanamido]-3-methylbutanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanoic acid; XH7F04LXTF; Angiotensin III trifluoroacetate salt hydrate; 1-De-L-aspartic acid-5-L-isoleucine-angiotensin II

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Angiotensin III. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000006590). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Angiotensin III (AngIII) is one of the N-terminal angiotensin degradation products of angiotensin II. AngIII shares some of its properties with Ang II, including chemotaxis and production of growth factors and chemokines. AngIII generated within the brain acts within neural circuits of the central nervous system to regulate body fluid balance. The stimulation of vasopressin release by AngIII is thought to be one of the mechanisms by which AngIII controls volume homeostasis under conditions of hypovolemia, by reducing renal water loss and increasing blood pressure. Brain aminopeptidase A, the enzyme forming central AngIII, could constitute a putative central therapeutic target for the treatment of hypertension. (PMID: 17210474, 11751722, 11295571).

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 12687-51-3
  • CAS Registry Number: 13602-53-4
  • PubChem: 3082042
  • ChEBI: ChEBI:1183270
  • ChEBI: ChEBI:89666
  • HMDB: HMDB0001036
  • HMDB: HMDB01036
  • KEGG: C15848
  • NCBI MeSH: Angiotensin III
  • Wikipedia: Angiotensin
  • Wikipedia: Angiotensin_III
  • RefMet: RM0136034
  • Metlin: METLIN_58017
  • Coconut NaturalProduct: CNP0084198.1

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
WikiPathways:WP376 Renin-angiotensin system
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